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The Science of Hydration: How Water Intake Affects Overall Health

  • rupahealth.com
  • Feb 28, 2024
  • 4 min read

Updated: Mar 1, 2024

Water is essential for life. Depending on age, the body is 55-75% water. However, about half of people worldwide don't meet daily water intake recommendations, and up to 75% of Americans are chronically dehydrated.


Understanding Hydration and the Human Body

Optimal hydration is paramount for maintaining overall health and well-being, and its importance extends far beyond simple thirst quenching. Water is required for the optimal physiological functioning of every organ system in the body. Water comprises 73% of the brain and heart, 31% of bones, 79% of muscles and kidneys, 64% of skin, and 83% of the lungs. Water is essential for maintaining cellular homeostasis, which refers to the body's ability to maintain a stable internal environment despite external fluctuations. The body keeps the balance of water and solutes within its cells and body fluids through osmoregulation. Maintaining an adequate hydration status influences this delicate balance, ensuring that cells neither swell nor shrink excessively, preserving their structural integrity and functionality.


Water is crucial for nutrient transport and absorption. It is a universal solvent, facilitating the dissolution and transportation of oxygen and essential vitamins, minerals, and other nutrients throughout the body.


Hydration is also integral to temperature regulation. The body relies on water to dissipate heat through perspiration, preventing overheating and maintaining a stable internal temperature. This is why staying well hydrated is especially important in hot weather.


Water acts as the body's natural lubricant. It cushions the joints to promote flexibility and mobility. Water also moistens the tissues of the eyes, nose, mouth, glands, skin, and digestive tract to prevent them from drying out. 

Water also aids digestive processes and helps to rid wastes from the body by supporting the detoxification and elimination functions of the kidneys, liver, and intestines.  


Cognitive function is influenced by hydration status. The brain needs water to create hormones and neurotransmitters responsible for thinking, processing, memory, and emotions. Water acts as a shock absorber for the brain and spinal cord, preventing injury.


Effects of Dehydration on Health


Dehydration occurs when the body loses more fluids than it takes in. This imbalance often results from inadequate water intake, excessive sweating, vomiting, diarrhea, or the use of diuretic medications. Infants, children, and adults over age 65 are at the highest risk of dehydration.


Dehydration can have profound and detrimental effects on health, affecting various physiological processes. It can hinder the efficient transport of nutrients and oxygen to cells and cause electrolyte imbalances, negatively impacting metabolic processes and cellular functioning. Inadequate hydration can impair cognitive function, causing difficulties in concentration, memory, and overall mental performance. It also compromises thermoregulation, making individuals more susceptible to heat-related illnesses like heatstroke. Dehydration may exacerbate joint issues by reducing the lubricating synovial fluid, contributing to stiffness and discomfort. Insufficient water intake can strain the kidneys and liver, impeding their detoxification functions and potentially leading to the accumulation of waste products and toxins in the body. Dehydrated skin is more prone to dryness and lacks the resilience needed to maintain a healthy protective barrier, potentially increasing the risk of dermatological issues. Severe dehydration can lead to shock, coma, and even death.


Given the potentially severe health consequences, it's important to recognize the signs and symptoms of dehydration. These symptoms may occur with as little as a 2% water deficit: 

  • Thirst

  • Dry mouth, skin, and lips

  • Fatigue

  • Flushed skin

  • Decreased urine volume or dark-colored urine

  • Headaches

  • Confusion

  • Irritability

  • Fast, racing heartbeat

  • Low blood pressure

  • Muscle cramps

  • Dizziness, especially when changing positions

  • Loss of appetite

  • Constipation


Hydration and Chronic Disease Prevention


The National Institutes of Health conducted a study involving 11,255 adults over 30 years, examining the relationship between serum sodium levels, hydration, and health outcomes. The research indicates that well-hydrated adults tend to be healthier, with fewer chronic conditions, and may live longer than those with insufficient fluid intake. Elevated serum sodium levels, even within the normal range, during middle age were associated with accelerated biological aging, an increased risk of chronic diseases, and premature mortality. Specifically, adults with serum sodium levels above 142 mEq/L had up to a 64% increased risk of heart failure, stroke, atrial fibrillation, peripheral artery disease, chronic lung disease, diabetes, and dementia. Adults with serum sodium levels between 138-140 mEq/L had the lowest risk of developing chronic disease. These findings underscore the importance of proper hydration in slowing aging, preventing chronic diseases, and promoting a disease-free life.


Adequate hydration exerts a profound influence on urinary system health. By promoting regular urine flow, hydration aids in flushing bacteria from the urinary tract. Studies consistently reveal that individuals maintaining proper hydration levels are less prone to urinary tract infections (UTIs) than those with lower fluid intake. Concerning kidney stones, hydration contributes significantly to prevention by maintaining higher urine volumes, thereby reducing the concentration of stone-forming substances and impeding their crystallization. Authors of a 2015 meta-analysis concluded that increased water intake is associated with a reduced risk of developing kidney stones. According to this analysis, consuming 2,000 mL and 3,100 mL of water daily is associated with a kidney stone risk reduction of 8% and 26%, respectively, compared to a daily water intake of 1,500 mL.


Water has been shown to be a protective factor in various types of cancer. Studies consistently suggest maintaining proper hydration is linked to a lower risk of colorectal cancer. Adequate water intake may contribute to regular bowel movements and prevent constipation, reducing the contact time between potential carcinogens and the colon lining. Data are more inconsistent for other types of cancer, but some studies do suggest that adequate fluid intake may be associated with a risk reduction for breast and bladder cancer.


Optimal Water Intake: How Much Is Enough?


The U.S. National Academies of Sciences, Engineering, and Medicine have determined an adequate daily fluid intake is approximately 2.7 liters (91 ounces) and 3.7 liters (125 ounces) for healthy women and men, respectively. About 80% of people's total water comes from drinking water and other beverages, and 20% is from food. For example, spinach and watermelon are almost 100% water by weight.

The National Academy of Medicine has established the following recommendations for daily water intake based on age group: 



Age

Daily Adequate Intake

1-3 years

4 cups (32 ounces)

4-8 years

5 cups (40 ounces)

9-13 years

7-8 cups (56-64 ounces)

14-18 years

8-11 cups(64-88 ounces)

Men 19+ years

13cups (104 ounces)

Women 19+ years

9 cups (72 ounces)

Pregnant women

10cups (80 ounces)

Breastfeeding Women

13cups (104 ounces)

As a general rule of thumb, your fluid intake is probably adequate if you rarely feel thirsty and your urine is colorless or light yellow. Drinking between 0.5-1 ounce of water for each pound you weigh daily is commonly recommended. For example, the average person who weighs 150 pounds should aim to drink between 75 and 150 ounces of water daily.


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